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Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation

The ubiquitous mammalian signaling molecule bisdiphosphoinositol tetrakisphosphate (1,5-(PP)(2)-myo-InsP(4), or InsP(8)) displays the most congested three-dimensional array of phosphate groups found in nature. The high charge density, the accumulation of unstable P-anhydrides and P-esters, the lack...

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Bibliografiset tiedot
Päätekijät: Capolicchio, Samanta, Wang, Huanchen, Thakor, Divyeshsinh T., Shears, Stephen B., Jessen, Henning J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153399/
https://ncbi.nlm.nih.gov/pubmed/25044992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404398
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