Antibodies as a model system for comparative model refinement

Por Sellers, Benjamin D., Nilmeier, Jerome P., Jacobson, Matthew P.
Publicado em 2010

Improving the species cross-reactivity of an antibody using computational design

Por Farady, Christopher J., Sellers, Benjamin D., Jacobson, Matthew P., Craik, Charles S.
Publicado em 2009

Toward better refinement of comparative models: Predicting loops in inexact environments

Por Sellers, Benjamin D., Zhu, Kai, Zhao, Suwen, Friesner, Richard A., Jacobson, Matthew P.
Publicado em 2008

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors

Por Sinitskiy, Anton V., Stanley, Nathaniel H., Hackos, David H., Hanson, Jesse E., Sellers, Benjamin D., Pande, Vijay S.
Publicado no Sci Rep (2017)

chemalot and chemalot_knime: Command line programs as workflow tools for drug discovery

Por Lee, Man-Ling, Aliagas, Ignacio, Feng, Jianwen A., Gabriel, Thomas, O’Donnell, T. J., Sellers, Benjamin D., Wiswedel, Bernd, Gobbi, Alberto
Publicado no J Cheminform (2017)

Conformation switching of clathrin light chain regulates clathrin lattice assembly

Por Wilbur, Jeremy D., Hwang, Peter K., Ybe, Joel A., Lane, Michael, Sellers, Benjamin D., Jacobson, Matthew P., Fletterick, Robert J., Brodsky, Frances M.
Publicado em 2010

Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2)

Por Pei, Zhonghua, Mendonca, Rohan, Gazzard, Lewis, Pastor, Richard, Goon, Leanne, Gustafson, Amy, VanderPorten, Erica, Hatzivassiliou, Georgia, Dement, Kevin, Cass, Robert, Yuen, Po-wai, Zhang, Yamin, Wu, Guosheng, Lin, Xingyu, Liu, Yichin, Sellers, Benjamin D.
Publicado no ACS Med Chem Lett (2018)

GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile

Por Villemure, Elisia, Volgraf, Matthew, Jiang, Yu, Wu, Guosheng, Ly, Cuong Q., Yuen, Po-wai, Lu, Aijun, Luo, Xifeng, Liu, Mingcui, Zhang, Shun, Lupardus, Patrick J., Wallweber, Heidi J. A., Liederer, Bianca M., Deshmukh, Gauri, Plise, Emile, Tay, Suzanne, Wang, Tzu-Ming, Hanson, Jesse E., Hackos, David H., Scearce-Levie, Kimberly, Schwarz, Jacob B., Sellers, Benjamin D.
Publicado no ACS Med Chem Lett (2016)

Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA

Por Alexander, Mary Kate, Miu, Anh, Oh, Angela, Reichelt, Mike, Ho, Hoangdung, Chalouni, Cecile, Labadie, Sharada, Wang, Lan, Liang, Jun, Nickerson, Nicholas N., Hu, Huiyong, Yu, Lan, Du, Miaofen, Yan, Donghong, Park, Summer, Kim, Janice, Xu, Min, Sellers, Benjamin D., Purkey, Hans E., Skelton, Nicholas J., Koehler, Michael F. T., Payandeh, Jian, Verma, Vishal, Xu, Yiming, Koth, Christopher M., Nishiyama, Mireille
Publicado no Antimicrob Agents Chemother (2018)

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models

Por Hanson, Jesse E., Ma, Keran, Elstrott, Justin, Weber, Martin, Saillet, Sandrine, Khan, Abdullah S., Simms, Jeffrey, Liu, Benjamin, Kim, Thomas A., Yu, Gui-Qiu, Chen, Yelin, Wang, Tzu-Ming, Jiang, Zhiyu, Liederer, Bianca M., Deshmukh, Gauri, Solanoy, Hilda, Chan, Connie, Sellers, Benjamin D., Volgraf, Matthew, Schwarz, Jacob B., Hackos, David H., Weimer, Robby M., Sheng, Morgan, Gill, T. Michael, Scearce-Levie, Kimberly, Palop, Jorge J.
Publicado no Cell Rep (2020)

Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors

Por Parr, Brendan T., Pastor, Richard, Sellers, Benjamin D., Pei, Zhonghua, Jaipuri, Firoz A., Castanedo, Georgette M., Gazzard, Lewis, Kumar, Sanjeev, Li, Xiaokai, Liu, Wen, Mendonca, Rohan, Pavana, Roheeth K., Potturi, Hima, Shao, Cheng, Velvadapu, Venkata, Waldo, Jesse P., Wu, Guosheng, Yuen, Po-wai, Zhang, Zuhui, Zhang, Yamin, Harris, Seth F., Oh, Angela J., DiPasquale, Antonio, Dement, Kevin, La, Hank, Goon, Leanne, Gustafson, Amy, VanderPorten, Erica C., Mautino, Mario R., Liu, Yichin
Publicado no ACS Med Chem Lett (2020)