GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile

af Villemure, Elisia, Volgraf, Matthew, Jiang, Yu, Wu, Guosheng, Ly, Cuong Q., Yuen, Po-wai, Lu, Aijun, Luo, Xifeng, Liu, Mingcui, Zhang, Shun, Lupardus, Patrick J., Wallweber, Heidi J. A., Liederer, Bianca M., Deshmukh, Gauri, Plise, Emile, Tay, Suzanne, Wang, Tzu-Ming, Hanson, Jesse E., Hackos, David H., Scearce-Levie, Kimberly, Schwarz, Jacob B., Sellers, Benjamin D.
Udgivet i ACS Med Chem Lett (2016)