Optimization of ADME Properties for Sulfonamides Leading to the Discovery of a T-Type Calcium Channel Blocker, ABT-639

Por Zhang, Qingwei, Xia, Zhiren, Joshi, Shailen, Scott, Victoria E., Jarvis, Michael F.
Publicado no ACS Med Chem Lett (2015)

Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K(+) channel Kir6.2 combination expressed in HEK-293 cells

Por Gopalakrishnan, Murali, Molinari, Eduardo J, Shieh, Char-Chang, Monteggia, Lisa M, Roch, Jean-Marc, Whiteaker, Kristi L, Scott, Victoria E S, Sullivan, James P, Brioni, Jorge D
Publicado em 2000

Pharmacological characterization of a 1,4-dihydropyridine analogue, 9-(3,4-dichlorophenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione (A-184209) as a novel...

Por Gopalakrishnan, Murali, Miller, Thomas R, Buckner, Steven A, Milicic, Ivan, Molinari, Eduardo J, Whiteaker, Kristi L, Davis-Taber, Rachel, Scott, Victoria E, Cassidy, Christopher, Sullivan, James P, Carroll, William A
Publicado em 2003

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-R(S)

Por Sun, Chaohong, Song, Danying, Davis-Taber, Rachel A., Barrett, Leo W., Scott, Victoria E., Richardson, Paul L., Pereda-Lopez, Ana, Uchic, Marie E., Solomon, Larry R., Lake, Marc R., Walter, Karl A., Hajduk, Philip J., Olejniczak, Edward T.
Publicado em 2007

In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K(+) channel opener, A-151892

Por Gopalakrishnan, Murali, Buckner, Steven A, Shieh, Char-Chang, Fey, Thomas, Fabiyi, Adebola, Whiteaker, Kristi L, Davis-Taber, Rachel, Milicic, Ivan, Daza, Anthony V, Scott, Victoria E S, Castle, Neil A, Printzenhoff, David, London, Brecht, Turner, Sean C, Carroll, William A, Sullivan, James P, Coghlan, Michael J, Brune, Michael E
Publicado em 2004