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Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K(+) channel Kir6.2 combination expressed in HEK-293 cells

1. The pharmacological properties of K(ATP) channels generated by stable co-expression of the sulphonylurea receptor SUR1 and the inwardly rectifying K(+) channel Kir6.2 were characterized in HEK-293 cells. 2. [(3)H]-Glyburide (glibenclamide) bound to transfected cells with a B(max) value of 18.5 pm...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gopalakrishnan, Murali, Molinari, Eduardo J, Shieh, Char-Chang, Monteggia, Lisa M, Roch, Jean-Marc, Whiteaker, Kristi L, Scott, Victoria E S, Sullivan, James P, Brioni, Jorge D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571965/
https://ncbi.nlm.nih.gov/pubmed/10742287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703181
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