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Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

All members of the inward rectifiier K(+) (Kir) channel family are activated by phosphoinositides and other amphiphilic lipids. To further elucidate the mechanistic basis, we examined the membrane association of Kir6.2 fragments of K(ATP) channels, and the effects of site-directed mutations of these...

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Bibliografiska uppgifter
Huvudupphovsmän: Cukras, Catherine A., Jeliazkova, Iana, Nichols, Colin G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233865/
https://ncbi.nlm.nih.gov/pubmed/12034765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028562
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