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Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains

Interactions between nontransmembrane domains and the lipid membrane are proposed to modulate activity of many ion channels. In Kir channels, the so-called “slide-helix” is proposed to interact with the lipid headgroups and control channel gating. We examined this possibility directly in a cell-free...

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Hlavní autoři: Enkvetchakul, Decha, Jeliazkova, Iana, Bhattacharyya, Jaya, Nichols, Colin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151642/
https://ncbi.nlm.nih.gov/pubmed/17698595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709764
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