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Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

All members of the inward rectifiier K(+) (Kir) channel family are activated by phosphoinositides and other amphiphilic lipids. To further elucidate the mechanistic basis, we examined the membrane association of Kir6.2 fragments of K(ATP) channels, and the effects of site-directed mutations of these...

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Autori principali: Cukras, Catherine A., Jeliazkova, Iana, Nichols, Colin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233865/
https://ncbi.nlm.nih.gov/pubmed/12034765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028562
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