Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-R(S)

The pituitary adenylate cyclase-activating polypeptide (PACAP) receptor is a class II G protein-coupled receptor that contributes to many different cellular functions including neurotransmission, neuronal survival, and synaptic plasticity. The solution structure of the potent antagonist PACAP (resid...

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Detalhes bibliográficos
Main Authors: Sun, Chaohong, Song, Danying, Davis-Taber, Rachel A., Barrett, Leo W., Scott, Victoria E., Richardson, Paul L., Pereda-Lopez, Ana, Uchic, Marie E., Solomon, Larry R., Lake, Marc R., Walter, Karl A., Hajduk, Philip J., Olejniczak, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876540/
https://ncbi.nlm.nih.gov/pubmed/17470806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611397104
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