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Pituitary adenylate cyclase–activating polypeptide is reduced in Alzheimer disease

OBJECTIVES: There is growing evidence that pituitary adenylate cyclase–activating polypeptide (PACAP) is associated with Alzheimer disease (AD) pathology in animal models, but human studies are needed. METHODS: We studied the brains of patients with pathologically confirmed late-onset AD and age-mat...

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Detalhes bibliográficos
Main Authors: Han, Pengcheng, Liang, Winnie, Baxter, Leslie C., Yin, Junxiang, Tang, Zhiwei, Beach, Thomas G., Caselli, Richard J., Reiman, Eric M., Shi, Jiong
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032204/
https://ncbi.nlm.nih.gov/pubmed/24719484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000417
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