The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide, Pathology and Cognition in Mice and Rhesus Macaques

Pituitary adenylate cyclase activating polypeptide (PACAP) is associated with Alzheimer’s disease (AD), but its age-related effects are unknown. We chose the rhesus macaque due to its closeness to human anatomy and physiology. We examined four variables: aging, cognitive performance, amyloid plaques...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Han, Pengcheng, Nielsen, Megan, Song, Melissa, Yin, Junxiang, Permenter, Michele R., Vogt, Julie A., Engle, James R., Dugger, Brittany N., Beach, Thomas G., Barnes, Carol A., Shi, Jiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467357/
https://ncbi.nlm.nih.gov/pubmed/28659785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00180
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