The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide, Pathology and Cognition in Mice and Rhesus Macaques

Pituitary adenylate cyclase activating polypeptide (PACAP) is associated with Alzheimer’s disease (AD), but its age-related effects are unknown. We chose the rhesus macaque due to its closeness to human anatomy and physiology. We examined four variables: aging, cognitive performance, amyloid plaques...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Han, Pengcheng, Nielsen, Megan, Song, Melissa, Yin, Junxiang, Permenter, Michele R., Vogt, Julie A., Engle, James R., Dugger, Brittany N., Beach, Thomas G., Barnes, Carol A., Shi, Jiong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467357/
https://ncbi.nlm.nih.gov/pubmed/28659785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00180
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