Mitochondrial RNA polymerase of Saccharomyces cerevisiae: composition and mechanism of promoter recognition.

Por Schinkel, A H, Groot Koerkamp, M J, Tabak, H F
Publicado em 1988

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Por Schinkel, A H, Wagenaar, E, Mol, C A, van Deemter, L
Publicado em 1996

P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

Por Schuetz, E G, Schinkel, A H, Relling, M V, Schuetz, J D
Publicado em 1996

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

Por Schinkel, A H, Wagenaar, E, van Deemter, L, Mol, C A, Borst, P
Publicado em 1995

RNA polymerase induces DNA bending at yeast mitochondrial promoters.

Por Schinkel, A H, Groot Koerkamp, M J, Teunissen, A W, Tabak, H F
Publicado em 1988

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833.

Por Mayer, U, Wagenaar, E, Dorobek, B, Beijnen, J H, Borst, P, Schinkel, A H
Publicado em 1997

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

Por Asperen, J van, Tellingen, O van, Tijssen, F, Schinkel, A H, Beijnen, J H
Publicado em 1999

Effect of point mutations on in vitro transcription from the promoter for the large ribosomal RNA gene of yeast mitochondria.

Por Schinkel, A H, Groot Koerkamp, M J, Stuiver, M H, Van der Horst, G T, Tabak, H F
Publicado em 1987

The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.

Por Tommasini, R, Evers, R, Vogt, E, Mornet, C, Zaman, G J, Schinkel, A H, Borst, P, Martinoia, E
Publicado em 1996

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Por Oude Elferink, R P, Ottenhoff, R, van Wijland, M, Smit, J J, Schinkel, A H, Groen, A K
Publicado em 1995

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

Por Jonker, J W, Wagenaar, E, van Deemter, L, Gottschlich, R, Bender, H M, Dasenbrock, J, Schinkel, A H
Publicado em 1999

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

Por van Asperen, J., van Tellingen, O., Sparreboom, A., Schinkel, A. H., Borst, P., Nooijen, W. J., Beijnen, J. H.
Publicado em 1997

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein.

Por Mayer, U., Wagenaar, E., Beijnen, J. H., Smit, J. W., Meijer, D. K., van Asperen, J., Borst, P., Schinkel, A. H.
Publicado em 1996

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation

Por Hendrikx, J J M A, Lagas, J S, Wagenaar, E, Rosing, H, Schellens, J H M, Beijnen, J H, Schinkel, A H
Publicado em 2014

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

Por Evers, R, Zaman, G J, van Deemter, L, Jansen, H, Calafat, J, Oomen, L C, Oude Elferink, R P, Borst, P, Schinkel, A H
Publicado em 1996

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

Por Hendrikse, N H, Schinkel, A H, De Vries, E G E, Fluks, E, Van der Graaf, W T A, Willemsen, A T M, Vaalburg, W, Franssen, E J F
Publicado em 1998

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

Por Evers, R, Kool, M, van Deemter, L, Janssen, H, Calafat, J, Oomen, L C, Paulusma, C C, Oude Elferink, R P, Baas, F, Schinkel, A H, Borst, P
Publicado em 1998

Characterization of the promoter of the large ribosomal RNA gene in yeast mitochondria and separation of mitochondrial RNA polymerase into two different functional components.

Por Schinkel, A H, Groot Koerkamp, M J, Van der Horst, G T, Touw, E P, Osinga, K A, Van der Bliek, A M, Veeneman, G H, Van Boom, J H, Tabak, H F
Publicado em 1986