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Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Disruption of the mdr2 gene in mice leads to a complete absence of phospholipid from bile (Smit, J. J. M., et al. 1993. Cell. 75:451-462). We have investigated the control of both mdr2 P-glycoprotein (Pgp) expression and bile salt secretion on biliary lipid secretion in the mouse. Lipid secretion wa...

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Detalhes bibliográficos
Main Authors: Oude Elferink, R P, Ottenhoff, R, van Wijland, M, Smit, J J, Schinkel, A H, Groen, A K
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295363/
https://ncbi.nlm.nih.gov/pubmed/7814632
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