Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Disruption of the mdr2 gene in mice leads to a complete absence of phospholipid from bile (Smit, J. J. M., et al. 1993. Cell. 75:451-462). We have investigated the control of both mdr2 P-glycoprotein (Pgp) expression and bile salt secretion on biliary lipid secretion in the mouse. Lipid secretion wa...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Oude Elferink, R P, Ottenhoff, R, van Wijland, M, Smit, J J, Schinkel, A H, Groen, A K
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117658
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