Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy

av Schönthal, Axel H.
Publicerad 2012

Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor

av Wu, Ray-Chang, Blumenthal, Martina, Li, Xinwei, Schönthal, Axel H
Publicerad 2002

Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy

av Chen, Thomas C, Fonseca, Clovis O Da, Schönthal, Axel H
I publikationen Am J Cancer Res (2015)

Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases

av Chen, Thomas C., Da Fonseca, Clovis O., Schönthal, Axel H.
I publikationen Int J Mol Sci (2016)

Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development

av Chen, Thomas C., da Fonseca, Clovis O., Schönthal, Axel H.
I publikationen Int J Mol Sci (2018)

NEO212: A NOVEL TEMOZOLOMIDE-PERILLYL ALCOHOL CONJUGATE EXHIBITS SUPERIOR ACTIVITY AGAINST TEMOZOLOMIDE RESISTANT GLIOMAS AND INTRACRANIAL TRIPLE NEGATIVE BREAST CANCER METASTASIS

av Chen, Thomas C., Schonthal, Axel H., Hofman, Florence M., Wang, Weijun, Cho, Heeyon
Publicerad 2014

COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro

av Chuang, Huan-Ching, Kardosh, Adel, Gaffney, Kevin J, Petasis, Nicos A, Schönthal, Axel H
Publicerad 2008

Increased Survivin Expression Confers Chemoresistance to Tumor-Associated Endothelial Cells

av Virrey, Jenilyn J., Guan, Shengxi, Li, Wei, Schönthal, Axel H., Chen, Thomas C., Hofman, Florence M.
Publicerad 2008

Role of BRCA1 in Controlling Mitotic Arrest in Ovarian Cystadenoma Cells

av Yu, Vanessa M., Marion, Christine M., Austria, Theresa M., Yeh, Jennifer, Schönthal, Axel H., Dubeau, Louis
Publicerad 2011

Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treat...

av Chen, Thomas C., Chan, Nymph, Minea, Radu O., Hartman, Hannah, Hofman, Florence M., Schönthal, Axel H.
I publikationen Cancers (Basel) (2018)

Increased Expression of TATA-Binding Protein, the Central Transcription Factor, Can Contribute to Oncogenesis

av Johnson, Sandra A. S., Dubeau, Louis, Kawalek, Michael, Dervan, Andrew, Schönthal, Axel H., Dang, Chi V., Johnson, Deborah L.
Publicerad 2003

ATPS-07 NEO214, ROLIPRAM CONJUGATED TO PERILLYL ALCOHOL, IS A NOVEL DRUG CYTOTOXIC FOR GLIOMAS BY TARGETING THE DEATH RECEPTOR MEDIATED TRAIL PATHWAY

av Cho, Hee-Yeon, Wang, Weijun, Huang, Mickey, Santiago, Shayane, Schönthal, Axel H., Hofman, Florence M., Chen, Thomas C.
I publikationen Neuro Oncol (2015)

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

av Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H.
I publikationen Int J Mol Sci (2018)

Perillyl alcohol: Dynamic interactions with the lipid bilayer and implications for long-term inhalational chemotherapy for gliomas

av da Fonseca, Clovis Orlando, Khandelia, Himanshu, Salazar, Marcela D’Alincourt, Schönthal, Axel H., Meireles, Osório C., Quirico-Santos, Thereza
I publikationen Surg Neurol Int (2016)

Mechanisms of G2 Arrest in Response to Overexpression of p53

av Taylor, William R., DePrimo, Samuel E., Agarwal, Archana, Agarwal, Munna L., Schönthal, Axel H., Katula, Karen S., Stark, George R.
Publicerad 1999

Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo

av Chen, Thomas C., Cho, Hee-Yeon, Wang, Weijun, Wetzel, Stephanie J., Singh, Anupam, Nguyen, Jenny, Hofman, Florence M., Schönthal, Axel H.
I publikationen J Biomed Sci (2015)

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo

av Swenson, Steve, Silva-Hirschberg, Catalina, Wang, Weijun, Singh, Anupam, Hofman, Florence M., Chen, Kristen L., Schönthal, Axel H., Chen, Thomas C.
I publikationen Oncotarget (2018)

Cytotoxic impact of a perillyl alcohol–temozolomide conjugate, NEO212, on cutaneous T-cell lymphoma in vitro

av Silva-Hirschberg, Catalina, Hartman, Hannah, Stack, Samantha, Swenson, Steve, Minea, Radu O., Davitz, Michael A., Chen, Thomas C., Schönthal, Axel H.
I publikationen Ther Adv Med Oncol (2019)

Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia

av Schönthal, Axel H., Swenson, Steve, Minea, Radu O., Kim, Hye Na, Cho, Heeyeon, Mohseni, Nazleen, Kim, Yong-Mi, Chen, Thomas C.
I publikationen Cancers (Basel) (2021)

Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I

av Thomas, Simmy, Sharma, Natasha, Gonzalez, Reyna, Pao, Peng-Wen, Hofman, Florence M., Chen, Thomas C., Louie, Stan G., Pirrung, Michael C., Schönthal, Axel H.
Publicerad 2013