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Role of BRCA1 in Controlling Mitotic Arrest in Ovarian Cystadenoma Cells
Cancers that develop in BRCA1 mutation carriers are usually near tetraploid/polyploid. This led us to hypothesize that BRCA1 controls the mitotic checkpoint complex, as loss of such control could lead to mitotic errors resulting in tetraploidy/polyploidy with subsequent aneuploidy. We used an in vit...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299830/ https://ncbi.nlm.nih.gov/pubmed/21792894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26309 |
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