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Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

Despite the introduction of new therapies for multiple myeloma (MM), many patients are still dying from this disease and novel treatments are urgently needed. We have designed a novel hybrid molecule, called NEO214, that was generated by covalent conjugation of the natural monoterpene perillyl alcoh...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796223/
https://ncbi.nlm.nih.gov/pubmed/29342125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010277
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