Toxoplasma Does Not Secrete the GRA16 and GRA24 Effectors Beyond the Parasitophorous Vacuole Membrane of Tissue Cysts

Por Krishnamurthy, Shruthi, Saeij, Jeroen P. J.
Publicado no Front Cell Infect Microbiol (2018)

Toxoplasma gondii Clonal Strains All Inhibit STAT1 Transcriptional Activity but Polymorphic Effectors Differentially Modulate IFNγ Induced Gene Expression and STAT1 Phosphorylation...

Por Rosowski, Emily E., Saeij, Jeroen P. J.
Publicado em 2012

Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits

Por Hassan, Musa A., Saeij, Jeroen P.J.
Publicado no Bioessays (2014)

A Cluster of Four Surface Antigen Genes Specifically Expressed in Bradyzoites, SAG2CDXY, Plays an Important Role in Toxoplasma gondii Persistence

Por Saeij, Jeroen P. J., Arrizabalaga, Gustavo, Boothroyd, John C.
Publicado em 2008

Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

Por Mukhopadhyay, Debanjan, Arranz-Solís, David, Saeij, Jeroen P. J.
Publicado no PLoS Pathog (2020)

Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection

Por Mukhopadhyay, Debanjan, Arranz-Solís, David, Saeij, Jeroen P. J.
Publicado no Front Cell Infect Microbiol (2020)

Toxoplasma gondii effectors are master regulators of the inflammatory response

Por Melo, Mariane B., Jensen, Kirk D.C., Saeij, Jeroen P.J.
Publicado em 2011

Toxoplasma and Plasmodium protein kinases: Roles in invasion and host cell remodelling

Por Lim, Daniel C., Cooke, Brian M., Doerig, Christian, Saeij, Jeroen P.J.
Publicado em 2011

The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages

Por Hassan, Musa A., Butty, Vincent, Jensen, Kirk D.C., Saeij, Jeroen P.J.
Publicado em 2014

Cell Death of Gamma Interferon-Stimulated Human Fibroblasts upon Toxoplasma gondii Infection Induces Early Parasite Egress and Limits Parasite Replication

Por Niedelman, Wendy, Sprokholt, Joris K., Clough, Barbara, Frickel, Eva-Maria, Saeij, Jeroen P. J.
Publicado em 2013

Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA

Por Rosowski, Emily E., Nguyen, Quynh P., Camejo, Ana, Spooner, Eric, Saeij, Jeroen P. J.
Publicado em 2014

Bioluminescence Imaging of Toxoplasma gondii Infection in Living Mice Reveals Dramatic Differences between Strains

Por Saeij, Jeroen P. J., Boyle, Jon P., Grigg, Michael E., Arrizabalaga, Gustavo, Boothroyd, John C.
Publicado em 2005

The human immune response to Toxoplasma: Autophagy versus cell death

Por Krishnamurthy, Shruthi, Konstantinou, Eleni K., Young, Lucy H., Gold, Daniel A., Saeij, Jeroen P. J.
Publicado no PLoS Pathog (2017)

Expression Quantitative Trait Locus Mapping of Toxoplasma Genes Reveals Multiple Mechanisms for Strain-Specific Differences in Gene Expression

Por Boyle, Jon P., Saeij, Jeroen P. J., Harada, Scott Y., Ajioka, Jim W., Boothroyd, John C.
Publicado em 2008

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

Por Reese, Michael L., Zeiner, Gusti M., Saeij, Jeroen P. J., Boothroyd, John C., Boyle, Jon P.
Publicado em 2011

De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding R...

Por Hassan, Musa A, Melo, Mariane B, Haas, Brian, Jensen, Kirk D C, Saeij, Jeroen P J
Publicado em 2012

Toxoplasma CRISPR/Cas9 constructs are functional for gene disruption in Neospora caninum

Por Arranz-Solís, David, Regidor-Cerrillo, Javier, Lourido, Sebastian, Ortega-Mora, Luis Miguel, Saeij, Jeroen P.J.
Publicado no Int J Parasitol (2018)

Toxoplasma GRA Peptide-Specific Serologic Fingerprints Discriminate Among Major Strains Causing Toxoplasmosis

Por Arranz-Solís, David, Carvalheiro, Cristina G., Zhang, Elizabeth R., Grigg, Michael E., Saeij, Jeroen P. J.
Publicado no Front Cell Infect Microbiol (2021)

Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity

Por Minot, Samuel, Melo, Mariane B., Li, Fugen, Lu, Diana, Niedelman, Wendy, Levine, Stuart S., Saeij, Jeroen P. J.
Publicado em 2012

Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection

Por Hassan, Musa A., Jensen, Kirk D., Butty, Vincent, Hu, Kenneth, Boedec, Erwan, Prins, Pjotr, Saeij, Jeroen P. J.
Publicado no PLoS Genet (2015)