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Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Mukhopadhyay, Debanjan, Arranz-Solís, David, Saeij, Jeroen P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274473/
https://ncbi.nlm.nih.gov/pubmed/32453782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008586
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