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Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Mukhopadhyay, Debanjan, Arranz-Solís, David, Saeij, Jeroen P. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274473/
https://ncbi.nlm.nih.gov/pubmed/32453782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008586
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