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Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Mukhopadhyay, Debanjan, Arranz-Solís, David, Saeij, Jeroen P. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274473/
https://ncbi.nlm.nih.gov/pubmed/32453782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008586
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