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Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11
The murine innate immune response against Toxoplasma gondii is predominated by the interaction of TLR11/12 with Toxoplasma profilin. However, mice lacking Tlr11 or humans, who do not have functional TLR11 or TLR12, still elicit a strong innate immune response upon Toxoplasma infection. The parasite...
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| Udgivet i: | PLoS Pathog |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274473/ https://ncbi.nlm.nih.gov/pubmed/32453782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008586 |
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