Cell Death of Gamma Interferon-Stimulated Human Fibroblasts upon Toxoplasma gondii Infection Induces Early Parasite Egress and Limits Parasite Replication

The intracellular protozoan parasite Toxoplasma gondii is a major food-borne illness and opportunistic infection for the immunosuppressed. Resistance to Toxoplasma is dependent on gamma interferon (IFN-γ) activation of both hematopoietic and nonhematopoietic cells. Although IFN-γ-induced innate immu...

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Detalhes bibliográficos
Main Authors: Niedelman, Wendy, Sprokholt, Joris K., Clough, Barbara, Frickel, Eva-Maria, Saeij, Jeroen P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837980/
https://ncbi.nlm.nih.gov/pubmed/24042117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00416-13
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