Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

IFN-γ is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma gondii. The p65 guanylate-binding proteins (GBPs) are strongly induced by IFN-γ. We studied the behavior of murine GBP1 (mGBP1) upon infection with T. gondii in vitro and confirmed that IFN-γ-dependent r...

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Detalhes bibliográficos
Main Authors: Virreira Winter, Sebastian, Niedelman, Wendy, Jensen, Kirk D., Rosowski, Emily E., Julien, Lindsay, Spooner, Eric, Caradonna, Kacey, Burleigh, Barbara A., Saeij, Jeroen P. J., Ploegh, Hidde L., Frickel, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169597/
https://ncbi.nlm.nih.gov/pubmed/21931713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024434
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