TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles

Interferon gamma (IFNγ) is the major proinflammatory cytokine conferring resistance to the intracellular vacuolar pathogen Toxoplasma gondii by inducing the destruction of the parasitophorous vacuole (PV). We previously identified TRIM21 as an IFNγ-driven E3 ubiquitin ligase mediating the deposition...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Foltz, Clémence, Napolitano, Anna, Khan, Rabia, Clough, Barbara, Hirst, Elizabeth M., Frickel, Eva-Maria
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507857/
https://ncbi.nlm.nih.gov/pubmed/28701773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05487-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items