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Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA

The gamma interferon (IFN-γ) response, mediated by the STAT1 transcription factor, is crucial for host defense against the intracellular pathogen Toxoplasma gondii, but prior infection with Toxoplasma can inhibit this response. Recently, it was reported that the Toxoplasma type II NTE strain prevent...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rosowski, Emily E., Nguyen, Quynh P., Camejo, Ana, Spooner, Eric, Saeij, Jeroen P. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911376/
https://ncbi.nlm.nih.gov/pubmed/24478085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01291-13
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