Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

Por Rosenbaum, Anton I., Maxfield, Frederick R.
Publicado em 2011

Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

Por Rosenbaum, Anton I., Zhang, Guangtao, Warren, J. David, Maxfield, Frederick R.
Publicado em 2010

CHEMICAL SCREEN TO REDUCE STEROL ACCUMULATION IN NIEMANN-PICK C DISEASE CELLS IDENTIFIES NOVEL LYSOSOMAL ACID LIPASE INHIBITORS

Por Rosenbaum, Anton I., Rujoi, Madalina, Huang, Amy Y., Du, Hong, Grabowski, Gregory A., Maxfield, Frederick R.
Publicado em 2009

Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann-Pick Type C Disease Therapeutics

Por Rosenbaum, Anton I., Cosner, Casey C., Mariani, Christopher J., Maxfield, Frederick R., Wiest, Olaf, Helquist, Paul
Publicado em 2010

Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics

Por Cosner, Casey C., Markiewicz, John T., Bourbon, Pauline, Mariani, Christopher J., Wiest, Olaf, Rujoi, Madalina, Rosenbaum, Anton, Huang, Amy, Maxfield, Frederick R., Helquist, Paul
Publicado em 2009