PARP3 comes to light as a prime target in cancer therapy

per Rodriguez-Vargas, José Manuel, Nguekeu-Zebaze, Léonel, Dantzer, Françoise
Publicat a Cell Cycle (2019)

PARP1 and Poly(ADP-ribosyl)ation Signaling during Autophagy in Response to Nutrient Deprivation

per Rodríguez-Vargas, José Manuel, Oliver-Pozo, Francisco Javier, Dantzer, Françoise
Publicat a Oxid Med Cell Longev (2019)

Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities

per Zamudio-Martinez, Esteban, Herrera-Campos, Ana Belén, Muñoz, Alberto, Rodríguez-Vargas, José Manuel, Oliver, F. Javier
Publicat a J Exp Clin Cancer Res (2021)

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

per Karicheva, Olga, Rodriguez-Vargas, José Manuel, Wadier, Nadège, Martin-Hernandez, Kathline, Vauchelles, Romain, Magroun, Najat, Tissier, Agnès, Schreiber, Valérie, Dantzer, Françoise
Publicat a Oncotarget (2016)

Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation

per Rodriguez-Vargas, José-Manuel, Martin-Hernandez, Kathline, Wang, Wei, Kunath, Nicolas, Suganthan, Rajikala, Amé, Jean-Christophe, Oliver, F. Javier, Ye, Jing, Bjørås, Magnar, Dantzer, Françoise
Publicat a Cell Death Dis (2020)

PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers

per Beck, Carole, Rodriguez-Vargas, José Manuel, Boehler, Christian, Robert, Isabelle, Heyer, Vincent, Hanini, Najat, Gauthier, Laurent R., Tissier, Agnès, Schreiber, Valérie, Elofsson, Mikael, Reina San Martin, Bernardo, Dantzer, Françoise
Publicat a Cell Death Differ (2018)

ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

per Rodríguez-Vargas, José Manuel, Ruiz-Magaña, María José, Ruiz-Ruiz, Carmen, Majuelos-Melguizo, Jara, Peralta-Leal, Andreína, Rodríguez, María Isabel, Muñoz-Gámez, José Antonio, de Almodóvar, Mariano Ruiz, Siles, Eva, Rivas, Abelardo López, Jäättela, Marja, Oliver, F Javier
Publicat 2012

PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

per Rodríguez, María Isabel, Peralta-Leal, Andreína, O'Valle, Francisco, Rodriguez-Vargas, José Manuel, Gonzalez-Flores, Ariannys, Majuelos-Melguizo, Jara, López, Laura, Serrano, Santiago, de Herreros, Antonio García, Rodríguez-Manzaneque, Juan Carlos, Fernández, Rubén, del Moral, Raimundo G., de Almodóvar, José Mariano, Oliver, F. Javier
Publicat 2013

Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions

per Martí, Juan Manuel, Garcia-Diaz, Angel, Delgado-Bellido, Daniel, O'Valle, Francisco, González-Flores, Ariannys, Carlevaris, Onintza, Rodríguez-Vargas, José Manuel, Amé, Jean Christophe, Dantzer, Françoise, King, George L., Dziedzic, Klaudia, Berra, Edurne, de Álava, E., Amaral, A.T., Hammond, Ester M., Oliver, F. Javier
Publicat a Redox Biol (2021)