PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation

PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however, the basis for the anti-metastasic activities resulting from PARP inhibition remains unknown. PARP inhibitors may also act as modulators of tum...

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Main Authors: Rodríguez, María Isabel, Peralta-Leal, Andreína, O'Valle, Francisco, Rodriguez-Vargas, José Manuel, Gonzalez-Flores, Ariannys, Majuelos-Melguizo, Jara, López, Laura, Serrano, Santiago, de Herreros, Antonio García, Rodríguez-Manzaneque, Juan Carlos, Fernández, Rubén, del Moral, Raimundo G., de Almodóvar, José Mariano, Oliver, F. Javier
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681683/
https://ncbi.nlm.nih.gov/pubmed/23785295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003531
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