PARP Inhibition Attenuates Histopathological Lesion in Ischemia/Reperfusion Renal Mouse Model after Cold Prolonged Ischemia

We test the hypothesis that PARP inhibition can decrease acute tubular necrosis (ATN) and other renal lesions related to prolonged cold ischemia/reperfusion (IR) in kidneys preserved at 4°C in University of Wisconsin (UW) solution. Material and Methods. We used 30 male Parp1(+/+) wild-type and 15 ma...

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Auteurs principaux: del Moral, Raimundo M. G., Gómez-Morales, Mercedes, Hernández-Cortés, Pedro, Aguilar, David, Caballero, Trinidad, Aneiros-Fernández, Jose, Caba-Molina, Mercedes, Rodríguez-Martínez, Mª  Dolores, Peralta, Andreina, Galindo-Moreno, Pablo, Osuna, Antonio, Oliver, F. Javier, del Moral, Raimundo G., O'Valle, Francisco
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844238/
https://ncbi.nlm.nih.gov/pubmed/24319370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/486574
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