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Post Ischemic PARP Inhibition Reduces Ischemia Reperfusion Injury in a Hind-Limb Ischemia Model
INTRODUCTION: These experiments were designed to determine whether systemic post ischemic administration of PJ34, a Poly ADP-ribose polymerase inhibitor, decreased tissue injury and inflammation following hind limb ischemia reperfusion (I/R). METHODS: C57BL6 mouse limbs were subjected to 1.5 hrs isc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886175/ https://ncbi.nlm.nih.gov/pubmed/20132957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.12.006 |
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