Postischemic Treatment With Ethyl Pyruvate Prevents Adenosine Triphosphate Depletion, Ameliorates Inflammation, and Decreases Thrombosis in a Murine Model of Hind-Limb Ischemia and Reperfusion

INTRODUCTION: Experiments were designed to investigate the effects of ethyl pyruvate (EP) in a murine model of hind-limb ischemia-reperfusion (IR) injury. METHODS: C57BL6 mice underwent 90 minutes of unilateral ischemia followed by 24 hours of reperfusion using two treatment protocols. For the preis...

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Main Authors: Crawford, Robert S., Albadawi, Hassan, Atkins, Marvin D., Jones, John J., Conrad, Mark F., Austen, William G., Fink, Mitchell P., Watkins, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056773/
https://ncbi.nlm.nih.gov/pubmed/21217488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e3182031ccb
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