Post Ischemic PARP Inhibition Reduces Ischemia Reperfusion Injury in a Hind-Limb Ischemia Model

INTRODUCTION: These experiments were designed to determine whether systemic post ischemic administration of PJ34, a Poly ADP-ribose polymerase inhibitor, decreased tissue injury and inflammation following hind limb ischemia reperfusion (I/R). METHODS: C57BL6 mouse limbs were subjected to 1.5 hrs isc...

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Detaylı Bibliyografya
Asıl Yazarlar: Crawford, Robert S., Albadawi, Hassan, Atkins, Marvin D., Jones, John E., Yoo, Hyung-Jin, Conrad, Mark F., Austen, W. Gerald, Watkins, Michael T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886175/
https://ncbi.nlm.nih.gov/pubmed/20132957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.12.006
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