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Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities
Tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2) are two homologous proteins that are gaining increasing importance due to their implication in multiple pathways and diseases such as cancer. TNKS1/2 interact with a large variety of substrates through the ankyrin (ANK) domain, which recognizes a sequence...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080362/ https://ncbi.nlm.nih.gov/pubmed/33910596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01950-6 |
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