γ-synuclein is a novel player in the control of body lipid metabolism

Por Millership, Steven, Ninkina, Natalia, Rochford, Justin J, Buchman, Vladimir L
Publicado em 2013

Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

Por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado no Sci Rep (2018)

Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Por Mcilroy, George D., Mitchell, Sharon E., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado no Dis Model Mech (2020)

Neuroanatomical Characterisation of the Expression of the Lipodystrophy and Motor-Neuropathy Gene Bscl2 in Adult Mouse Brain

Por Garfield, Alastair S., Chan, Wai S., Dennis, Rowena J., Ito, Daisuke, Heisler, Lora K., Rochford, Justin J.
Publicado em 2012

Promethin Is a Conserved Seipin Partner Protein

Por Castro, Inês G., Eisenberg-Bord, Michal, Persiani, Elisa, Rochford, Justin J., Schuldiner, Maya, Bohnert, Maria
Publicado no Cells (2019)

The burden of metabolic syndrome on osteoarthritic joints

Por Dickson, Bruce M., Roelofs, Anke J., Rochford, Justin J., Wilson, Heather M., De Bari, Cosimo
Publicado no Arthritis Res Ther (2019)

Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2

Por Grimsey, Neil, Han, Gil-Soo, O'Hara, Laura, Rochford, Justin J., Carman, George M., Siniossoglou, Symeon
Publicado em 2008

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

Por Talukder, Md. Mesbah Uddin, Sim, M.F. Michelle, O'Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.
Publicado no Mol Metab (2015)

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

Por Sim, M. F. Michelle, Talukder, M. Mesbah Uddin, Dennis, Rowena J., O’Rahilly, Stephen, Edwardson, J. Michael, Rochford, Justin J.
Publicado em 2013

Serotonin 5-HT(2C) Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

Por Lam, Daniel D., Przydzial, Magdalena J., Ridley, Simon H., Yeo, Giles S. H., Rochford, Justin J., O’Rahilly, Stephen, Heisler, Lora K.
Publicado em 2008

C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis

Por PAYNE, Victoria A., AU, Wo-Shing, LOWE, Christopher E., RAHMAN, Shaikh M., FRIEDMAN, Jacob E., O’RAHILLY, Stephen, ROCHFORD, Justin J.
Publicado em 2009

Knockdown of Diacylglycerol Kinase Delta Inhibits Adipocyte Differentiation and Alters Lipid Synthesis

Por LOWE, Christopher E., ZHANG, Qifeng, DENNIS, Rowena J., AUBRY, Evelyne A., O’RAHILLY, Stephen, WAKELAM, Michael J.O., ROCHFORD, Justin J.
Publicado em 2013

Role of the POZ Zinc Finger Transcription Factor FBI-1 in Human and Murine Adipogenesis

Por Laudes, Matthias, Christodoulides, Constantinos, Sewter, Ciaran, Rochford, Justin J., Considine, Robert V., Sethi, Jaswinder K., Vidal-Puig, Antonio, O’Rahilly, Stephen
Publicado no J Biol Chem (2003)

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

Por Sim, M. F. Michelle, Persiani, Elisa, Talukder, Md. Mesbah Uddin, Mcilroy, George D., Roumane, Ahlima, Edwardson, J. Michael, Rochford, Justin J.
Publicado no Sci Rep (2020)

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential for Normal Adipocyte Differentiation

Por Payne, Victoria A., Grimsey, Neil, Tuthill, Antoinette, Virtue, Sam, Gray, Sarah L., Nora, Edoardo Dalla, Semple, Robert K., O'Rahilly, Stephen, Rochford, Justin J.
Publicado em 2008

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1

Por Sim, M.F. Michelle, Dennis, Rowena J., Aubry, Evelyne M., Ramanathan, Nardev, Sembongi, Hiroshi, Saudek, Vladimir, Ito, Daisuke, O'Rahilly, Stephen, Siniossoglou, Symeon, Rochford, Justin J.
Publicado em 2012

SEQUENTIAL REGULATION OF DGAT2 EXPRESSION BY C/EBPβ AND C/EBPα DURING ADIPOGENESIS

Por Payne, Victoria A., Au, Wo-Shing, Gray, Sarah L., Nora, Edoardo Dalla, Rahman, Shaikh M., Sanders, Rebecca, Hadaschik, Dirk, Friedman, Jacob E., O'Rahilly, Stephen, Rochford, Justin J.
Publicado em 2007

Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity

Por Millership, Steven, Ninkina, Natalia, Guschina, Irina A., Norton, Jessica, Brambilla, Riccardo, Oort, Pieter J., Adams, Sean H., Dennis, Rowena J., Voshol, Peter J., Rochford, Justin J., Buchman, Vladimir L.
Publicado em 2012

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

Por Mcilroy, George D., Suchacki, Karla, Roelofs, Anke J., Yang, Wulin, Fu, Yanyun, Bai, Bo, Wallace, Robert J., De Bari, Cosimo, Cawthorn, William P., Han, Weiping, Delibegović, Mirela, Rochford, Justin J.
Publicado no Mol Metab (2018)

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells

Por Georgescu, Teodora, Lyons, David, Doslikova, Barbora, Garcia, Ana Paula, Marston, Oliver, Burke, Luke K, Chianese, Raffaella, Lam, Brian Y H, Yeo, Giles S H, Rochford, Justin J, Garfield, Alastair S, Heisler, Lora K
Publicado no Endocrinology (2020)