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Serotonin 5-HT(2C) Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors

The neurotransmitter serotonin (5-hydroxytryptamine) is a well-established modulator of energy balance. Both pharmacological and genetic evidence implicate the serotonin 2C receptor (5-HT(2C)R) as a critical receptor mediator of serotonin’s effects on ingestive behavior. Here we characterized the ef...

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Bibliographic Details
Main Authors: Lam, Daniel D., Przydzial, Magdalena J., Ridley, Simon H., Yeo, Giles S. H., Rochford, Justin J., O’Rahilly, Stephen, Heisler, Lora K.
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275368/
https://ncbi.nlm.nih.gov/pubmed/18039773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1321
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