The L-Type Amino Acid Transporter LAT1—An Emerging Target in Cancer

di Pascal Häfliger, Roch-Philippe Charles
Pubblicazione 2019-05-01

The L-Type Amino Acid Transporter LAT1—An Emerging Target in Cancer

di Häfliger, Pascal, Charles, Roch-Philippe
Pubblicato in Int J Mol Sci (2019)

Antiprotozoan and Antiviral Activities of Non-cytotoxic Truncated and Variant Analogues of Mussel Defensin

di Roch, Philippe, Beschin, Alain, Bernard, Eric
Pubblicazione 2004

Stratégie nationale suisse de la conservation /

di Roch, Philippe, Duvanel, Laurent, Goujon, Sylvain
Pubblicazione c1988

Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

di Charles, Roch-Philippe, Iezza, Gioia, Amendola, Elena, Dankort, David, McMahon, Martin
Pubblicazione 2011

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

di Kind, Marcus, Klukowska-Rötzler, Jolanta, Berezowska, Sabina, Arcaro, Alexandre, Charles, Roch-Philippe
Pubblicato in PLoS One (2017)

Activating BRAF and PIK3CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis

di Charles, Roch-Philippe, Silva, Jillian, Iezza, Gioia, Phillips, Wayne A., McMahon, Martin
Pubblicato in Mol Cancer Res (2014)

The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes

di Yang, Hsin-ya, Charles, Roch-Philippe, Hummler, Edith, Baines, Deborah L., Isseroff, R. Rivkah
Pubblicazione 2013

4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation

di Chicca, Andrea, Gachet, Maria Salomé, Petrucci, Vanessa, Schuehly, Wolfgang, Charles, Roch-Philippe, Gertsch, Jürg
Pubblicato in J Neuroinflammation (2015)

Massively Parallel Amplicon Sequencing Reveals Isotype-Specific Variability of Antimicrobial Peptide Transcripts in Mytilus galloprovincialis

di Rosani, Umberto, Varotto, Laura, Rossi, Alberta, Roch, Philippe, Novoa, Beatriz, Figueras, Antonio, Pallavicini, Alberto, Venier, Paola
Pubblicazione 2011

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

di Leyvraz, Céline, Charles, Roch-Philippe, Rubera, Isabelle, Guitard, Marjorie, Rotman, Samuel, Breiden, Bernadette, Sandhoff, Konrad, Hummler, Edith
Pubblicazione 2005

The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model

di Häfliger, Pascal, Graff, Julien, Rubin, Matthias, Stooss, Amandine, Dettmer, Matthias S., Altmann, Karl-Heinz, Gertsch, Jürg, Charles, Roch-Philippe
Pubblicato in J Exp Clin Cancer Res (2018)

E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor

di Li, Chun-Ying, Cha, Wanghee, Luder, Hans-Ulrich, Charles, Roch-Philippe, McMahon, Martin, Mitsiadis, Thimios, Klein, Ophir D.
Pubblicazione 2012

PIK3CA(H1047R)-induced paradoxical ERK activation results in resistance to BRAF(V600E) specific inhibitors in BRAF(V600E) PIK3CA(H1047R) double mutant thyroid tumors

di Roelli, Matthias A., Ruffieux-Daidié, Dorothée, Stooss, Amandine, ElMokh, Oussama, Phillips, Wayne A., Dettmer, Matthias S., Charles, Roch-Philippe
Pubblicato in Oncotarget (2017)

PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models

di Nisa, Lluís, Häfliger, Pascal, Poliaková, Michaela, Giger, Roland, Francica, Paola, Aebersold, Daniel Matthias, Charles, Roch-Philippe, Zimmer, Yitzhak, Medová, Michaela
Pubblicato in Mol Cancer (2017)

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

di Hummler, Edith, Dousse, Aline, Rieder, Audrey, Stehle, Jean-Christophe, Rubera, Isabelle, Osterheld, Maria-Chiara, Beermann, Friedrich, Frateschi, Simona, Charles, Roch-Philippe
Pubblicazione 2013

Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance

di Malsure, Sumedha, Wang, Qing, Charles, Roch-Philippe, Sergi, Chloe, Perrier, Romain, Christensen, Birgitte Mønster, Maillard, Marc, Rossier, Bernard C., Hummler, Edith
Pubblicazione 2014

Combined MEK and Pi3′-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

di ElMokh, Oussama, Ruffieux-Daidié, Dorothée, Roelli, Matthias A, Stooss, Amandine, Phillips, Wayne A, Gertsch, Jürg, Dettmer, Matthias S, Charles, Roch-Philippe
Pubblicato in Oncotarget (2017)

Insights into the innate immunity of the Mediterranean mussel Mytilus galloprovincialis

di Venier, Paola, Varotto, Laura, Rosani, Umberto, Millino, Caterina, Celegato, Barbara, Bernante, Filippo, Lanfranchi, Gerolamo, Novoa, Beatriz, Roch, Philippe, Figueras, Antonio, Pallavicini, Alberto
Pubblicazione 2011

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1

di Planès, Carole, Randrianarison, Nadia H, Charles, Roch-Philippe, Frateschi, Simona, Cluzeaud, Françoise, Vuagniaux, Grégoire, Soler, Paul, Clerici, Christine, Rossier, Bernard C, Hummler, Edith
Pubblicazione 2010