The L-Type Amino Acid Transporter LAT1—An Emerging Target in Cancer

Por Pascal Häfliger, Roch-Philippe Charles
Publicado em 2019-05-01

The L-Type Amino Acid Transporter LAT1—An Emerging Target in Cancer

Por Häfliger, Pascal, Charles, Roch-Philippe
Publicado no Int J Mol Sci (2019)

Stratégie nationale suisse de la conservation /

Por Roch, Philippe, Duvanel, Laurent, Goujon, Sylvain
Publicado em c198

Antiprotozoan and Antiviral Activities of Non-cytotoxic Truncated and Variant Analogues of Mussel Defensin

Por Roch, Philippe, Beschin, Alain, Bernard, Eric
Publicado em 2004

Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

Por Charles, Roch-Philippe, Iezza, Gioia, Amendola, Elena, Dankort, David, McMahon, Martin
Publicado em 2011

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis

Por Kind, Marcus, Klukowska-Rötzler, Jolanta, Berezowska, Sabina, Arcaro, Alexandre, Charles, Roch-Philippe
Publicado no PLoS One (2017)

Activating BRAF and PIK3CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis

Por Charles, Roch-Philippe, Silva, Jillian, Iezza, Gioia, Phillips, Wayne A., McMahon, Martin
Publicado no Mol Cancer Res (2014)

The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes

Por Yang, Hsin-ya, Charles, Roch-Philippe, Hummler, Edith, Baines, Deborah L., Isseroff, R. Rivkah
Publicado em 2013

4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation

Por Chicca, Andrea, Gachet, Maria Salomé, Petrucci, Vanessa, Schuehly, Wolfgang, Charles, Roch-Philippe, Gertsch, Jürg
Publicado no J Neuroinflammation (2015)

Massively Parallel Amplicon Sequencing Reveals Isotype-Specific Variability of Antimicrobial Peptide Transcripts in Mytilus galloprovincialis

Por Rosani, Umberto, Varotto, Laura, Rossi, Alberta, Roch, Philippe, Novoa, Beatriz, Figueras, Antonio, Pallavicini, Alberto, Venier, Paola
Publicado em 2011

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

Por Leyvraz, Céline, Charles, Roch-Philippe, Rubera, Isabelle, Guitard, Marjorie, Rotman, Samuel, Breiden, Bernadette, Sandhoff, Konrad, Hummler, Edith
Publicado em 2005

The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model

Por Häfliger, Pascal, Graff, Julien, Rubin, Matthias, Stooss, Amandine, Dettmer, Matthias S., Altmann, Karl-Heinz, Gertsch, Jürg, Charles, Roch-Philippe
Publicado no J Exp Clin Cancer Res (2018)

E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor

Por Li, Chun-Ying, Cha, Wanghee, Luder, Hans-Ulrich, Charles, Roch-Philippe, McMahon, Martin, Mitsiadis, Thimios, Klein, Ophir D.
Publicado em 2012

PIK3CA(H1047R)-induced paradoxical ERK activation results in resistance to BRAF(V600E) specific inhibitors in BRAF(V600E) PIK3CA(H1047R) double mutant thyroid tumors

Por Roelli, Matthias A., Ruffieux-Daidié, Dorothée, Stooss, Amandine, ElMokh, Oussama, Phillips, Wayne A., Dettmer, Matthias S., Charles, Roch-Philippe
Publicado no Oncotarget (2017)

PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models

Por Nisa, Lluís, Häfliger, Pascal, Poliaková, Michaela, Giger, Roland, Francica, Paola, Aebersold, Daniel Matthias, Charles, Roch-Philippe, Zimmer, Yitzhak, Medová, Michaela
Publicado no Mol Cancer (2017)

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Por Hummler, Edith, Dousse, Aline, Rieder, Audrey, Stehle, Jean-Christophe, Rubera, Isabelle, Osterheld, Maria-Chiara, Beermann, Friedrich, Frateschi, Simona, Charles, Roch-Philippe
Publicado em 2013

Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance

Por Malsure, Sumedha, Wang, Qing, Charles, Roch-Philippe, Sergi, Chloe, Perrier, Romain, Christensen, Birgitte Mønster, Maillard, Marc, Rossier, Bernard C., Hummler, Edith
Publicado em 2014

Combined MEK and Pi3′-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

Por ElMokh, Oussama, Ruffieux-Daidié, Dorothée, Roelli, Matthias A, Stooss, Amandine, Phillips, Wayne A, Gertsch, Jürg, Dettmer, Matthias S, Charles, Roch-Philippe
Publicado no Oncotarget (2017)

Insights into the innate immunity of the Mediterranean mussel Mytilus galloprovincialis

Por Venier, Paola, Varotto, Laura, Rosani, Umberto, Millino, Caterina, Celegato, Barbara, Bernante, Filippo, Lanfranchi, Gerolamo, Novoa, Beatriz, Roch, Philippe, Figueras, Antonio, Pallavicini, Alberto
Publicado em 2011

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1

Por Planès, Carole, Randrianarison, Nadia H, Charles, Roch-Philippe, Frateschi, Simona, Cluzeaud, Françoise, Vuagniaux, Grégoire, Soler, Paul, Clerici, Christine, Rossier, Bernard C, Hummler, Edith
Publicado em 2010