The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

The serine protease CAP1/Prss8 is crucial for skin barrier function, lung alveolar fluid clearance and has been unveiled as diagnostic marker for specific cancer types. Here, we show that a constitutive knockout of CAP1/Prss8 leads to embryonic lethality. These embryos presented no specific defects,...

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Main Authors: Hummler, Edith, Dousse, Aline, Rieder, Audrey, Stehle, Jean-Christophe, Rubera, Isabelle, Osterheld, Maria-Chiara, Beermann, Friedrich, Frateschi, Simona, Charles, Roch-Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565977/
https://ncbi.nlm.nih.gov/pubmed/23405214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055796
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