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Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis
PI3K signaling is frequently dysregulated in NSCLC-SQCC. In contrast to well characterized components of the PI3K signaling network contributing to the formation of SQCC, potential oncogenic effects of alterations in PIK3C2B are poorly understood. Here, a large cohort (n = 362) of NSCLC-SQCC was sel...
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Publicado no: | PLoS One |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5663493/ https://ncbi.nlm.nih.gov/pubmed/29088297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187308 |
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