The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS

av Rhoads, Shannon N., Monahan, Zachary T., Yee, Debra S., Shewmaker, Frank P.
I publikationen Int J Mol Sci (2018)

Yeast Models of Prion-Like Proteins That Cause Amyotrophic Lateral Sclerosis Reveal Pathogenic Mechanisms

av Monahan, Zachary T., Rhoads, Shannon N., Yee, Debra S., Shewmaker, Frank P.
I publikationen Front Mol Neurosci (2018)

The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization

av Rhoads, Shannon N., Monahan, Zachary T., Yee, Debra S., Leung, Andrew Y., Newcombe, Cameron G., O’Meally, Robert N., Cole, Robert N., Shewmaker, Frank P.
I publikationen Mol Biol Cell (2018)

A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing

av Wang, Ailin, Conicella, Alexander E, Schmidt, Hermann Broder, Martin, Erik W, Rhoads, Shannon N, Reeb, Ashley N, Nourse, Amanda, Ramirez Montero, Daniel, Ryan, Veronica H, Rohatgi, Rajat, Shewmaker, Frank, Naik, Mandar T, Mittag, Tanja, Ayala, Yuna M, Fawzi, Nicolas L
I publikationen EMBO J (2018)

Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity

av Monahan, Zachary, Ryan, Veronica H, Janke, Abigail M, Burke, Kathleen A, Rhoads, Shannon N, Zerze, Gül H, O'Meally, Robert, Dignon, Gregory L, Conicella, Alexander E, Zheng, Wenwei, Best, Robert B, Cole, Robert N, Mittal, Jeetain, Shewmaker, Frank, Fawzi, Nicolas L
I publikationen EMBO J (2017)