Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast

Por Reijns, Martin A M, Auchynnikava, Tatsiana, Beggs, Jean D
Publicado em 2009

Requirements for nuclear localization of Lsm2-8p and competition between nuclear and cytoplasmic Lsm complexes

Por Spiller, Michael P., Reijns, Martin A. M., Beggs, Jean D.
Publicado em 2007

Genome-wide mapping of embedded ribonucleotides and other non-canonical nucleotides using emRiboSeq and EndoSeq

Por Ding, James, Taylor, Martin S., Jackson, Andrew P., Reijns, Martin A. M.
Publicado no Nat Protoc (2015)

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA

Por Spiller, Michael P., Boon, Kum-Loong, Reijns, Martin A. M., Beggs, Jean D.
Publicado em 2007

A role for Q/N-rich aggregation-prone regions in P-body localization

Por Reijns, Martin A. M., Alexander, Ross D., Spiller, Michael P., Beggs, Jean D.
Publicado em 2008

Lagging strand replication shapes the mutational landscape of the genome

Por Reijns, Martin A. M., Kemp, Harriet, Ding, James, de Procé, Sophie Marion, Jackson, Andrew P., Taylor, Martin S.
Publicado no Nature (2015)

PCNA directs type 2 RNase H activity on DNA replication and repair substrates

Por Bubeck, Doryen, Reijns, Martin A. M., Graham, Stephen C., Astell, Katy R., Jones, E. Yvonne, Jackson, Andrew P.
Publicado em 2011

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

Por Reijns, Martin A. M., Bubeck, Doryen, Gibson, Lucien C. D., Graham, Stephen C., Baillie, George S., Jones, E. Yvonne, Jackson, Andrew P.
Publicado em 2011

Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin.

Por Hiller, Björn, Hoppe, Anja, Haase, Christa, Hiller, Christina, Schubert, Nadja, Müller, Werner, Reijns, Martin A. M., Jackson, Andrew P., Kunkel, Thomas A., Wenzel, Jörg, Behrendt, Rayk, Roers, Axel
Publicado no Cancer Res (2018)

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

Por Rigby, Rachel E, Webb, Lauren M, Mackenzie, Karen J, Li, Yue, Leitch, Andrea, Reijns, Martin A M, Lundie, Rachel J, Revuelta, Ailsa, Davidson, Donald J, Diebold, Sandra, Modis, Yorgo, MacDonald, Andrew S, Jackson, Andrew P
Publicado em 2014

Human and Mouse Mutations in WDR35 Cause Short-Rib Polydactyly Syndromes Due to Abnormal Ciliogenesis

Por Mill, Pleasantine, Lockhart, Paul J., Fitzpatrick, Elizabeth, Mountford, Hayley S., Hall, Emma A., Reijns, Martin A.M., Keighren, Margaret, Bahlo, Melanie, Bromhead, Catherine J., Budd, Peter, Aftimos, Salim, Delatycki, Martin B., Savarirayan, Ravi, Jackson, Ian J., Amor, David J.
Publicado em 2011

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

Por Moss, Chloe F., Dalla Rosa, Ilaria, Hunt, Lilian E., Yasukawa, Takehiro, Young, Robert, Jones, Aleck W. E., Reddy, Kaalak, Desai, Radha, Virtue, Sam, Elgar, Greg, Voshol, Peter, Taylor, Martin S., Holt, Ian J., Reijns, Martin A. M., Spinazzola, Antonella
Publicado no Nucleic Acids Res (2017)

cGAS surveillance of micronuclei links genome instability to innate immunity

Por Mackenzie, Karen J., Carroll, Paula, Martin, Carol-Anne, Murina, Olga, Fluteau, Adeline, Simpson, Daniel, Olova, Nelly, Sutcliffe, Hannah, Rainger, Jacqueline, Robertson, Andrea, Osborn, Ruby, Wheeler, Ann, Nowotny, Marcin, Gilbert, Nick, Chandra, Tamir, Reijns, Martin A. M., Jackson, Andrew P.
Publicado no Nature (2017)

Biallelic variants in DNA2 cause microcephalic primordial dwarfism

Por Tarnauskaitė, Žygimantė, Bicknell, Louise S., Marsh, Joseph A., Murray, Jennie E., Parry, David A., Logan, Clare V., Bober, Michael B., de Silva, Deepthi C., Duker, Angela L., Sillence, David, Wise, Carol, Jackson, Andrew P., Murina, Olga, Reijns, Martin A. M.
Publicado no Hum Mutat (2019)

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

Por Reijns, Martin A.M., Rabe, Björn, Rigby, Rachel E., Mill, Pleasantine, Astell, Katy R., Lettice, Laura A., Boyle, Shelagh, Leitch, Andrea, Keighren, Margaret, Kilanowski, Fiona, Devenney, Paul S., Sexton, David, Grimes, Graeme, Holt, Ian J., Hill, Robert E., Taylor, Martin S., Lawson, Kirstie A., Dorin, Julia R., Jackson, Andrew P.
Publicado em 2012

Synonymous mutations in RNASEH2A create cryptic splice sites impairing RNase H2 enzyme function in Aicardi-Goutières syndrome

Por Rice, Gillian I., Reijns, Martin A.M., Coffin, Stephanie R., Forte, Gabriella M.A., Anderson, Beverley H., Szynkiewicz, Marcin, Gornall, Hannah, Gent, David, Leitch, Andrea, Botella, Maria P., Fazzi, Elisa, Gener, Blanca, Lagae, Lieven, Olivieri, Ivana, Orcesi, Simona, Swoboda, Kathryn J., Perrino, Fred W., Jackson, Andrew P., Crow, Yanick J.
Publicado em 2013

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Por Zimmermann, Michal, Murina, Olga, Reijns, Martin A. M., Agathanggelou, Angelo, Challis, Rachel, Tarnauskaitė, Žygimantė, Muir, Morwenna, Fluteau, Adeline, Aregger, Michael, McEwan, Andrea, Yuan, Wei, Clarke, Matthew, Lambros, Maryou B., Paneesha, Shankara, Moss, Paul, Chandrashekhar, Megha, Angers, Stephane, Moffat, Jason, Brunton, Valerie G., Hart, Traver, de Bono, Johann, Stankovic, Tatjana, Jackson, Andrew P., Durocher, Daniel
Publicado no Nature (2018)

Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

Por Heyn, Patricia, Logan, Clare V., Fluteau, Adeline, Challis, Rachel C., Auchynnikava, Tatsiana, Martin, Carol-Anne, Marsh, Joseph A., Taglini, Francesca, Kilanowski, Fiona, Parry, David A., Cormier-Daire, Valerie, Fong, Chin-To, Gibson, Kate, Hwa, Vivian, Ibáñez, Lourdes, Robertson, Stephen P., Sebastiani, Giorgia, Rappsilber, Juri, Allshire, Robin C., Reijns, Martin A.M., Dauber, Andrew, Sproul, Duncan, Jackson, Andrew P.
Publicado no Nat Genet (2018)

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

Por Aden, Konrad, Bartsch, Kareen, Dahl, Joseph, Reijns, Martin A.M., Esser, Daniela, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Wottawa, Felix, Ito, Go, Mishra, Neha, Knittler, Katharina, Burkholder, Adam, Welz, Lina, van Es, Johan, Tran, Florian, Lipinski, Simone, Kakavand, Nassim, Boeger, Christine, Lucius, Ralph, von Schoenfels, Witigo, Schafmayer, Clemens, Lenk, Lennart, Chalaris, Athena, Clevers, Hans, Röcken, Christoph, Kaleta, Christoph, Rose-John, Stefan, Schreiber, Stefan, Kunkel, Thomas, Rabe, Björn, Rosenstiel, Philip
Publicado no Gastroenterology (2019)

TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism

Por Harley, Margaret E., Murina, Olga, Leitch, Andrea, Higgs, Martin R., Bicknell, Louise S., Yigit, Gökhan, Blackford, Andrew N., Zlatanou, Anastasia, Mackenzie, Karen J., Reddy, Kaalak, Halachev, Mihail, McGlasson, Sarah, Reijns, Martin A. M., Fluteau, Adeline, Martin, Carol-Anne, Sabbioneda, Simone, Elcioglu, Nursel H., Altmüller, Janine, Thiele, Holger, Greenhalgh, Lynn, Chessa, Luciana, Maghnie, Mohamad, Salim, Mahmoud, Bober, Michael B., Nürnberg, Peter, Jackson, Stephen P., Hurles, Matthew E., Wollnik, Bernd, Stewart, Grant S., Jackson, Andrew P.
Publicado no Nat Genet (2015)