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Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin.

Due to imperfect discrimination against ribonucleoside triphosphates by the replicative DNA polymerases, large numbers of ribonucleotides are incorporated into the eukaryotic nuclear genome during S-phase. Ribonucleotides, by far the most common DNA lesion in replicating cells, destabilize the DNA,...

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Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Hiller, Björn, Hoppe, Anja, Haase, Christa, Hiller, Christina, Schubert, Nadja, Müller, Werner, Reijns, Martin A. M., Jackson, Andrew P., Kunkel, Thomas A., Wenzel, Jörg, Behrendt, Rayk, Roers, Axel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526525/
https://ncbi.nlm.nih.gov/pubmed/30154151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1099
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