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Genome-wide mapping of embedded ribonucleotides and other non-canonical nucleotides using emRiboSeq and EndoSeq

Ribonucleotides are the most common non-canonical nucleotides incorporated into the genome of replicating cells. They are efficiently removed by ribonucleotide excision repair initiated by Ribonuclease (RNase) H2 cleavage. In the absence of RNase H2, such embedded ribonucleotides can be used to trac...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Ding, James, Taylor, Martin S., Jackson, Andrew P., Reijns, Martin A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876909/
https://ncbi.nlm.nih.gov/pubmed/26313479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.099
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