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Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA

Abundant ribonucleotide incorporation in DNA during replication and repair has profound consequences for genome stability, but the global distribution of ribonucleotide incorporation is unknown. We developed Ribose-seq, a method to capture unique products generated by alkaline cleavage of DNA at emb...

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Bibliografische gegevens
Gepubliceerd in:Nat Methods
Hoofdauteurs: Koh, Kyung Duk, Balachander, Sathya, Hesselberth, Jay R., Storici, Francesca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686381/
https://ncbi.nlm.nih.gov/pubmed/25622106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3259
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