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Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA

Abundant ribonucleotide incorporation in DNA during replication and repair has profound consequences for genome stability, but the global distribution of ribonucleotide incorporation is unknown. We developed Ribose-seq, a method to capture unique products generated by alkaline cleavage of DNA at emb...

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Détails bibliographiques
Publié dans:Nat Methods
Auteurs principaux: Koh, Kyung Duk, Balachander, Sathya, Hesselberth, Jay R., Storici, Francesca
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686381/
https://ncbi.nlm.nih.gov/pubmed/25622106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3259
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