Update on biomarkers in systemic sclerosis: tools for diagnosis and treatment

Por Affandi, Alsya J., Radstake, Timothy R. D. J., Marut, Wioleta
Publicado no Semin Immunopathol (2015)

Genetics of Systemic Sclerosis: An Update

Por Broen, Jasper C. A., Coenen, Marieke J. H., Radstake, Timothy R. D. J.
Publicado em 2011

Fc Gamma Receptor IIb on GM-CSF Macrophages Controls Immune Complex Mediated Inhibition of Inflammatory Signals

Por Santegoets, Kim C. M., Wenink, Mark H., van den Berg, Wim B., Radstake, Timothy R. D. J.
Publicado em 2014

Morphea and Eosinophilic Fasciitis: An Update

Por Mertens, Jorre S., Seyger, Marieke M. B., Thurlings, Rogier M., Radstake, Timothy R. D. J., de Jong, Elke M. G. J.
Publicado no Am J Clin Dermatol (2017)

The Pronounced Th17 Profile in Systemic Sclerosis (SSc) Together with Intracellular Expression of TGFβ and IFNγ Distinguishes SSc Phenotypes

Por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Hussiani, Anila, Hesselstrand, Roger, Wuttge, Dirk M., Deng, Yanhui, Simms, Robbert, Lubberts, Erik, Lafyatis, Robert
Publicado em 2009

Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression

Por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Wenink, Mark, Santegoets, Kim, Deng, Yanhui, Hussaini, Anila, Simms, Robert, Cruikshank, William W., Lafyatis, Robert
Publicado em 2009

Soluble Immune Complexes Shift the TLR-Induced Cytokine Production of Distinct Polarized Human Macrophage Subsets towards IL-10

Por Ambarus, Carmen A., Santegoets, Kim C. M., van Bon, Lenny, Wenink, Mark H., Tak, Paul P., Radstake, Timothy R. D. J., Baeten, Dominique L. P.
Publicado em 2012

Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin

Por Mathes, Allison L, Christmann, Romy B, Stifano, Giuseppina, Affandi, Alsya J, Radstake, Timothy R D J, Farina, G Alessandra, Padilla, Cristina, McLaughlin, Sarah, Lafyatis, Robert
Publicado em 2013

Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis

Por Farina, Giuseppina Alessandra, York, Michael, Di Marzio, Mike, Collins, Cindy, Meller, Stephan, Homey, Bernhard, Rifkin, Ian R., Marshak-Rothstein, Ann, Radstake, Timothy R.D.J., Lafyatis, Robert
Publicado em 2010

Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors

Por Ciechomska, Marzena, Huigens, Christiaan A, Hügle, Thomas, Stanly, Tess, Gessner, Andreas, Griffiths, Bridget, Radstake, Timothy R D J, Hambleton, Sophie, O'Reilly, Steven, van Laar, Jacob M
Publicado em 2013

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade

Por Hillen, Maarten R., Hartgring, Sarita A. Y., Willis, Cynthia R., Radstake, Timothy R. D. J., Hack, Cornelis E., Lafeber, Floris P. J. G., van Roon, Joel A. G
Publicado no PLoS One (2015)

Circulating levels of the chemokine CCL18 but not CXCL16 are elevated and correlate with disease activity in rheumatoid arthritis

Por van Lieshout, Antoine W T, Fransen, Jaap, Flendrie, Marcel, Eijsbouts, Agnes M M, van den Hoogen, Frank H J, van Riel, Piet L C M, Radstake, Timothy R D J
Publicado em 2007

Can baseline serum microRNAs predict response to TNF-alpha inhibitors in rheumatoid arthritis?

Por Cuppen, Bart V. J., Rossato, Marzia, Fritsch-Stork, Ruth D. E., Concepcion, Arno N., Schenk, Yolande, Bijlsma, Johannes W. J., Radstake, Timothy R. D. J., Lafeber, Floris P. J. G.
Publicado no Arthritis Res Ther (2016)

Macrophage migration inhibitory factor polymorphisms do not predict therapeutic response to glucocorticoids or to tumour necrosis factor α‐neutralising treatments in rheumatoid art...

Por Radstake, Timothy R D J, Fransen, Jaap, Toonen, Erik J M, Coenen, Marieke J H, Eijsbouts, Agnes E, Donn, Rachelle, van den Hoogen, Frank H J, van Riel, Piet L C M
Publicado em 2007

Aberrant leukocyte telomere length in Birdshot Uveitis

Por Vazirpanah, Nadia, Verhagen, Fleurieke H., Rothova, Anna, Missotten, Tom O. A. R., van Velthoven, Mirjam, Den Hollander, Anneke I., Hoyng, Carel B., Radstake, Timothy.R. D. J., Broen, Jasper C. A., Kuiper, Jonas J. W.
Publicado no PLoS One (2017)

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

Por Abdollahi-Roodsaz, Shahla, Joosten, Leo A.B., Koenders, Marije I., Devesa, Isabel, Roelofs, Mieke F., Radstake, Timothy R.D.J., Heuvelmans-Jacobs, Marleen, Akira, Shizuo, Nicklin, Martin J.H., Ribeiro-Dias, Fátima, van den Berg, Wim B.
Publicado em 2007

Modulation of lipoprotein plasma concentrations during long‐term anti‐TNF therapy in patients with active rheumatoid arthritis

Por Popa, Calin, van den Hoogen, Frank H J, Radstake, Timothy R D J, Netea, Mihai G, Eijsbouts, Agnes E, den Heijer, Martin, van der Meer, Jos W M, van Riel, Piet L C M, Stalenhoef, Anton F H, Barrera, Pilar
Publicado em 2007

Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis

Por Garcia, Samuel, Hartkamp, Linda M., Malvar-Fernandez, B, van Es, Inge E., Lin, Haishan, Wong, Justin, Long, Li, Zanghi, James A., Rankin, Andrew L., Masteller, Emma L., Wong, Brian R., Radstake, Timothy R. D. J., Tak, Paul P., Reedquist, Kris A.
Publicado no Arthritis Res Ther (2016)

Validation Study of Existing Gene Expression Signatures for Anti-TNF Treatment in Patients with Rheumatoid Arthritis

Por Toonen, Erik J. M., Gilissen, Christian, Franke, Barbara, Kievit, Wietske, Eijsbouts, Agnes M., den Broeder, Alfons A., van Reijmersdal, Simon V., Veltman, Joris A., Scheffer, Hans, Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Barrera, Pilar, Coenen, Marieke J. H.
Publicado em 2012

Novel Association in Chromosome 4q27 Region with Rheumatoid Arthritis and Confirmation of Type 1 Diabetes Point to a General Risk Locus for Autoimmune Diseases

Por Zhernakova, Alexandra , Alizadeh, Behrooz Z. , Bevova, Marianna , Leeuwen, Miek A. van , Coenen, Marieke J. H. , Franke, Barbara , Franke, Lude , Posthumus, Marcel D. , Heel, David A. van , Steege, Gerrit van der , Radstake, Timothy R. D. J. , Barrera, Pilar , Roep, Bart O. , Koeleman, Bobby P. C. , Wijmenga, Cisca 
Publicado em 2007