Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis

Immune activation of fibrosis likely plays a crucial role in the pathogenesis of systemic sclerosis (SSc). The goal of this study was to better understand innate immune regulation and associated IFN- and TGFβ-responsive gene expression in SSc skin and dermal fibroblasts, in particular the effect of...

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מידע ביבליוגרפי
Main Authors: Farina, Giuseppina Alessandra, York, Michael, Di Marzio, Mike, Collins, Cindy, Meller, Stephan, Homey, Bernhard, Rifkin, Ian R., Marshak-Rothstein, Ann, Radstake, Timothy R.D.J., Lafyatis, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086558/
https://ncbi.nlm.nih.gov/pubmed/20613770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.200
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