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CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin

Toll-like receptor 9 (TLR9) drives innate immune responses after recognition of foreign or endogenous DNA containing unmethylated CpG motifs. DNA-mediated TLR9 activation is highly implicated in the pathogenesis of several autoimmune skin diseases, yet its contribution to the inflammation seen in th...

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Dettagli Bibliografici
Pubblicato in:Exp Dermatol
Autori principali: Mathes, Allison L., Rice, Lisa, Affandi, Alsya J., DiMarzio, Michael, Rifkin, Ian R., Stifano, Giuseppina, Christmann, Romy B., Lafyatis, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474603/
https://ncbi.nlm.nih.gov/pubmed/25425469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12603
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