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CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin
Toll-like receptor 9 (TLR9) drives innate immune responses after recognition of foreign or endogenous DNA containing unmethylated CpG motifs. DNA-mediated TLR9 activation is highly implicated in the pathogenesis of several autoimmune skin diseases, yet its contribution to the inflammation seen in th...
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| Publicado no: | Exp Dermatol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474603/ https://ncbi.nlm.nih.gov/pubmed/25425469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12603 |
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