Soluble Immune Complexes Shift the TLR-Induced Cytokine Production of Distinct Polarized Human Macrophage Subsets towards IL-10

BACKGROUND: Costimulation of murine macrophages with immune complexes (ICs) and TLR ligands leads to alternative activation. Studies on human myeloid cells, however, indicate that ICs induce an increased pro-inflammatory cytokine production. This study aimed to clarify the effect of ICs on the pro-...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ambarus, Carmen A., Santegoets, Kim C. M., van Bon, Lenny, Wenink, Mark H., Tak, Paul P., Radstake, Timothy R. D. J., Baeten, Dominique L. P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338562/
https://ncbi.nlm.nih.gov/pubmed/22563430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035994
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