Profile of a Serial Killer: Cellular and Molecular Approaches to Study Individual Cytotoxic T-Cells following Therapeutic Vaccination

Por Iancu, Emanuela M., Baumgaertner, Petra, Wieckowski, Sébastien, Speiser, Daniel E., Rufer, Nathalie
Publicado em 2011

Identification and isolation of high avidity tumor-specific CD8 T cells by experimentally assessing pMHC-TCR binding parameters with soluble pMHC complexes

Por Schmidt, Julien, Hebeisen, Michael, Guillaume, Philippe, Magnin, Morgane, Rufer, Nathalie, Luescher, Immanuel
Publicado no J Immunother Cancer (2015)

Molecular Insights for Optimizing T Cell Receptor Specificity Against Cancer

Por Hebeisen, Michael, Oberle, Susanne G., Presotto, Danilo, Speiser, Daniel E., Zehn, Dietmar, Rufer, Nathalie
Publicado em 2013

Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

Por Hebeisen, Michael, Allard, Mathilde, Gannon, Philippe O., Schmidt, Julien, Speiser, Daniel E., Rufer, Nathalie
Publicado no Front Immunol (2015)

Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen

Por Speiser, Daniel E., Baumgaertner, Petra, Voelter, Verena, Devevre, Estelle, Barbey, Catherine, Rufer, Nathalie, Romero, Pedro
Publicado em 2008

Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo

Por Mahnke, Yolanda D., Devevre, Estelle, Baumgaertner, Petra, Matter, Maurice, Rufer, Nathalie, Romero, Pedro, Speiser, Daniel E.
Publicado em 2012

SHP-1 phosphatase activity counteracts increased T cell receptor affinity

Por Hebeisen, Michael, Baitsch, Lukas, Presotto, Danilo, Baumgaertner, Petra, Romero, Pedro, Michielin, Olivier, Speiser, Daniel E., Rufer, Nathalie
Publicado em 2013

Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

Por Rufer, Nathalie, Brümmendorf, Tim H., Kolvraa, Steen, Bischoff, Claus, Christensen, Kaare, Wadsworth, Louis, Schulzer, Michael, Lansdorp, Peter M.
Publicado em 1999

TCRep 3D: An Automated In Silico Approach to Study the Structural Properties of TCR Repertoires

Por Leimgruber, Antoine, Ferber, Mathias, Irving, Melita, Hussain-Kahn, Hamid, Wieckowski, Sébastien, Derré, Laurent, Rufer, Nathalie, Zoete, Vincent, Michielin, Olivier
Publicado em 2011

Heterogeneity assessment of functional T cell avidity

Por Ioannidou, Kalliopi, Baumgaertner, Petra, Gannon, Philippe O., Speiser, Michel F., Allard, Mathilde, Hebeisen, Michael, Rufer, Nathalie, Speiser, Daniel E.
Publicado no Sci Rep (2017)

Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes

Por Speiser, Daniel E., Wieckowski, Sébastien, Gupta, Bhawna, Iancu, Emanuela M., Baumgaertner, Petra, Baitsch, Lukas, Michielin, Olivier, Romero, Pedro, Rufer, Nathalie
Publicado em 2011

An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain

Por Voelter, Verena, Pica, Alessia, Laurent, Julien, Rimoldi, Donata, Bouzourene, Hanifa, Sajadi, Ali, Matter, Maurice, Romero, Pedro, Rufer, Nathalie, Speiser, Daniel E.
Publicado em 2008

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients

Por Iancu, Emanuela M., Gannon, Philippe O., Laurent, Julien, Gupta, Bhawna, Romero, Pedro, Michielin, Olivier, Romano, Emanuela, Speiser, Daniel E., Rufer, Nathalie
Publicado em 2013

Rapid and strong human CD8(+) T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

Por Speiser, Daniel E., Liénard, Danielle, Rufer, Nathalie, Rubio-Godoy, Verena, Rimoldi, Donata, Lejeune, Ferdy, Krieg, Arthur M., Cerottini, Jean-Charles, Romero, Pedro
Publicado em 2005

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8(+) T Cell Responsiveness

Por Irving, Melita, Zoete, Vincent, Hebeisen, Michael, Schmid, Daphné, Baumgartner, Petra, Guillaume, Philippe, Romero, Pedro, Speiser, Daniel, Luescher, Immanuel, Rufer, Nathalie, Michielin, Olivier
Publicado em 2012

Distinct sets of αβ TCRs confer similar recognition of tumor antigen NY-ESO-1(157–165) by interacting with its central Met/Trp residues

Por Derré, Laurent, Bruyninx, Marc, Baumgaertner, Petra, Ferber, Mathias, Schmid, Daphné, Leimgruber, Antoine, Zoete, Vincent, Romero, Pedro, Michielin, Olivier, Speiser, Daniel E., Rufer, Nathalie
Publicado em 2008

Exhaustion of tumor-specific CD8(+) T cells in metastases from melanoma patients

Por Baitsch, Lukas, Baumgaertner, Petra, Devêvre, Estelle, Raghav, Sunil K., Legat, Amandine, Barba, Leticia, Wieckowski, Sébastien, Bouzourene, Hanifa, Deplancke, Bart, Romero, Pedro, Rufer, Nathalie, Speiser, Daniel E.
Publicado em 2011

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

Por Baitsch, Lukas, Legat, Amandine, Barba, Leticia, Fuertes Marraco, Silvia A., Rivals, Jean-Paul, Baumgaertner, Petra, Christiansen-Jucht, Céline, Bouzourene, Hanifa, Rimoldi, Donata, Pircher, Hanspeter, Rufer, Nathalie, Matter, Maurice, Michielin, Olivier, Speiser, Daniel E.
Publicado em 2012

Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans

Por Zippelius, Alfred, Pittet, Mikaël J., Batard, Pascal, Rufer, Nathalie, de Smedt, Magda, Guillaume, Philippe, Ellefsen, Kim, Valmori, Danila, Liénard, Danielle, Plum, Jean, MacDonald, H. Robson, Speiser, Daniel E., Cerottini, Jean-Charles, Romero, Pedro
Publicado em 2002

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer

Por Bron, Sylvian, Henry, Luc, Faes-van't Hull, Eveline, Turrini, Riccardo, Vanhecke, Dominique, Guex, Nicolas, Ifticene-Treboux, Assia, Marina Iancu, Emanuela, Semilietof, Aikaterini, Rufer, Nathalie, Lehr, Hans-Anton, Xenarios, Ioannis, Coukos, George, Delaloye, Jean-François, Doucey, Marie-Agnès
Publicado no Oncoimmunology (2015)